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1

Administration of Tauroursodeoxycholic Acid (TUDCA) Reduces Apoptosis Following Myocardial Infarction in Rat

Rivard, Andrew L., Steer, Clifford J., Kren, Betsy T., Rodrigues, Cecilia M. P., Castro, Rui E., Bianco, Richard W., Low, Walter C.

Journal:

The American Journal of Chinese Medicine

Year:

2007

Language:

english

File:

PDF, 1.43 MB

english, 2007

2

Tauroursodeoxycholic Acid Partially Prevents Apoptosis Induced by 3-Nitropropionic Acid : Evidence for a Mitochondrial Pathway Independent of the Permeability Transition

Cecilia M. P. Rodrigues, Cheryle Linehan- Stieers, C. Dirk Keene, Xiaoming Ma, Betsy T. Kren, Walter C. Low, Clifford J. Steer

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 438 KB

english, 2000

3

Regulation of bile acid synthesis by deoxycholic acid in the rat: Different effects on cholesterol 7α-hydroxylase and sterol 27-hydroxylase

Sarah Shefer, Betsy T. Kren, Gerald Salen, Clifford J. Steer, Lien B. Nguyen, Thomas Chen, G. Stephen Tint, Ashok K. Batta

Journal:

Year:

1995

Language:

english

File:

PDF, 982 KB

english, 1995

4

[Methods in Enzymology] Gene Therapy Methods Volume 346 || [2] Oligonucleotide-mediated site-directed gene repair

Year:

2002

Language:

english

File:

PDF, 1.22 MB

english, 2002

5

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

Janeen H. Trembley, Gretchen M. Unger, Vicci L. Korman, Diane K. Tobolt, Zygmunt Kazimierczuk, Lorenzo A. Pinna, Betsy T. Kren, Khalil Ahmed

Journal:

Year:

2012

Language:

english

File:

PDF, 842 KB

english, 2012

6

Ursodeoxycholic Acid May Inhibit Deoxycholic Acid-Induced Apoptosis by Modulating Mitochondrial Transmembrane Potential and Reactive Oxygen Species Production

Rodrigues, Cecilia M. P., Fan, Guangsheng, Wong, Phillip Y., Kren, Betsy T., Steer, Clifford J.

Journal:

Molecular Medicine

Year:

1998

Language:

english

File:

PDF, 2.35 MB

english, 1998

7

Gene therapy as an alternative to liver transplantation

Betsy T. Kren, Namita Roy Chowdhury, Jayanta Roy Chowdhury, Clifford J. Steer

Journal:

Liver Transplantation

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

8

Gene Repair and Transposon-Mediated Gene Therapy

Paul D. Richardson, Lance B. Augustin, Betsy T. Kren, Clifford J. Steer

Journal:

Year:

2002

Language:

english

File:

PDF, 256 KB

english, 2002

9

Ethanol interferes with regeneration-associated changes in biotransforming enzymes: A potential mechanism underlying ethanol's carcinogenicity?

Anna Mae Diehl, Hanna Cathrine Bisgaard, Betsy T. Kren, Clifford J. Steer

Journal:

Year:

1991

Language:

english

File:

PDF, 762 KB

english, 1991

10

37. Comparison of gene expression in vivo from Sleeping Beauty transposons after hydrodynamic delivery or condensation by polyethylenimine and cationic lipids

Perry Hackett, Kelly Podetz-Pedersen, Jason Bell, Elena Aronovich, Betsy Kren, Chester Whitley, Wouter Driessen, Sean Sullivan, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 45 KB

english, 2008

11

Genomic organization and promoter characterization of the rat cyclin B1 gene

Janeen H. Trembley, Zongyu Chen, Cecilia M.P. Rodrigues, Betsy T. Kren, Clifford J. Steer

Journal:

Year:

2000

Language:

english

File:

PDF, 343 KB

english, 2000

12

884 Ursodeoxycholic acid modulates the RB/E2F-1 apoptotic pathway in rat hepatocytes as determined by microarray analysis

Rui E. Castro, Susana Sola, Betsy T. Kren, Clifford J. Steer, Cecilia M.P. Rodrigues

Journal:

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

13

Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation

Chang Won Park, Zongyu Chen, Betsy T. Kren, Clifford J. Steer

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 636 KB

english, 2004

14

Protein Kinase CK2 Inhibition Induces Cell Death via Early Impact on Mitochondrial Function

Qaiser, Fatima, Trembley, Janeen H., Kren, Betsy T., Wu, Jing-Jiang, Naveed, A. Khaliq, Ahmed, Khalil

Journal:

Journal of Cellular Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.65 MB

english, 2014

15

Therapeutic targeting of protein kinase CK2 gene expression in feline oral squamous cell carcinoma - a naturally occurring large animal model of head and neck cancer

Cannon, Claire, Trembley, Janeen, Kren, Betsy, Unger, Gretchen, O'Sullivan, M. Gerard, Cornax, Ingrid, Modiano, Jaime, Ahmed, Khalil

Journal:

Human Gene Therapy Clinical Development

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

16

Protein kinase CK2 impact on intracellular calcium homeostasis in prostate cancer

Afzal, Muhammad, Kren, Betsy T., Naveed, A. Khaliq, Trembley, Janeen H., Ahmed, Khalil

Journal:

Molecular and Cellular Biochemistry

Year:

2020

File:

PDF, 5.75 MB

2020

17

In Vivo Application of Non-viral Vectors to the Liver

Richardson, Paul, Kren, Betsy T., Steer, Clifford J.

Journal:

Journal of Drug Targeting

Year:

2002

Language:

english

File:

PDF, 1.57 MB

english, 2002

18

Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice

Trembley, Janeen H., Unger, Gretchen M., Korman, Vicci L., Abedin, Md. Joynal, Nacusi, Lucas P., Vogel, Rachel I., Slaton, Joel W., Kren, Betsy T., Ahmed, Khalil, Munirathinam, Gnanasekar

Journal:

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

19

β-globin matrix attachment region improves stable genomic expression of the Sleeping beauty transposon

Lucas Sjeklocha, Yixin Chen, Meghan C. Daly, Clifford J. Steer, Betsy T. Kren

Journal:

Journal of Cellular Biochemistry

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

20

Changes in cell cycle-associated gene expression in a model of impaired liver regeneration

Jeffrey H. Albrecht, Jeffrey S. Hoffman, Betsy T. Kren, Clifford J. Steer

Journal:

Year:

1994

Language:

english

File:

PDF, 732 KB

english, 1994

21

Short, single-stranded oligonucleotides mediate targeted nucleotide conversion using extracts from isolated liver mitochondria

Betsy T. Kren, Phillip Y. Wong, Clifford J. Steer

Journal:

Year:

2003

Language:

english

File:

PDF, 228 KB

english, 2003

22

184 Ursodeoxycholic acid prevents TGF-β1-induced apoptosis through modulation of the glucocorticoid receptor in primary rat hepatocytes

Susana Sola, Rui E. Castro, Betsy T. Kren, Clifford J. Steer, Cecilia M.P. Rodrigues

Journal:

Year:

2003

Language:

english

File:

PDF, 122 KB

english, 2003

23

Correction of the UDP-Glucuronosyltransferase Gene Defect in the Gunn Rat Model of Crigler-Najjar Syndrome Type I with a Chimeric Oligonucleotide

Betsy T. Kren, Bhupesh Parashar, Paramita Bandyopadhyay, Namita Roy Chowdhury, Jayanta Roy Chowdhury and Clifford J. Steer

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.85 MB

english, 1999

24

The site-specific delivery of ursodeoxycholic acid to the rat colon by sulfate conjugation

Cecilia M.P. Rodrigues, Betsy T. Kren, Clifford J. Steer, Kenneth D.R. Setchell

Journal:

Gastroenterology

Year:

1995

Language:

english

File:

PDF, 1.07 MB

english, 1995

25

Escherichia coli glutaredoxin: cloning and overexpression, thermodynamic stability of the oxidized and reduced forms, and report of an N-terminal extended species

Sandberg, Victoria A., Kren, Betsy, Fuchs, James A., Woodward, Clare

Journal:

Year:

1991

Language:

english

File:

PDF, 1.82 MB

english, 1991

26

CK2 Molecular Targeting—Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer

Trembley, Janeen, Kren, Betsy, Abedin, Md., Vogel, Rachel, Cannon, Claire, Unger, Gretchen, Ahmed, Khalil

Journal:

Pharmaceuticals

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

27

Evaluation of a new high-dimensional miRNA profiling platform

Julie M Cunningham, Ann L Oberg, Pedro M Borralho, Betsy T Kren, Amy J French, Liang Wang, Brian M Bot, Bruce W Morlan, Kevin AT Silverstein, Rod Staggs, Yan Zeng, Anne-Francoise Lamblin, Christopher

Journal:

BMC Medical Genomics

Year:

2009

Language:

english

File:

PDF, 2.22 MB

english, 2009

28

W1862 Proteoliposomes Containing Sendai Virus F-Glycoprotein for Hepatocyte-Targeted Gene Therapy of the Gunn Rat Model of Crigler-Najjar Syndrome Type 1

Wang, Xia, Sarkar, Debi P., Mani, Prashant, Steer, Clifford J., Kren, Betsy T., Moitra, Rituparna, Chen, Yong, Roy-Chowdhury, Namita, Roy-Chowdhury, Jayanta

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 145 KB

english, 2008

29

Differential Regulation of Multiple Gap Junction Transcripts and Proteins during Rat Liver Regeneration

Betsy T. Kren, Nalin M. Kumar, Sheng-qi Wang, Norton B. Gilula and Clifford J. Steer

Journal:

The Journal of Cell Biology

Year:

1993

Language:

english

File:

PDF, 2.31 MB

english, 1993

30

Gene Repair Using Chimeric RNA/DNA Oligonucleotides

Kren, Betsy, Metz, Richard, Kumar, Ramesh, Steer, Clifford

Journal:

Seminars in Liver Disease

Year:

1999

Language:

english

File:

PDF, 1.26 MB

english, 1999

31

Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

Rodrigues, Cecilia MP, Ma, Xiaoming, Linehan-Stieers, Cheryle, Fan, Guangsheng, Kren, Betsy T, Steer, Clifford J

Journal:

Cell Death & Differentiation

Year:

1999

Language:

english

File:

PDF, 770 KB

english, 1999

32

A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid

Rui E. Castro, Susana Solá, Xiaoming Ma, Rita M. Ramalho, Betsy T. Kren, Clifford J. Steer, Cecília M.P. Rodrigues

Journal:

Journal of Hepatology

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

33

Gene therapy and CVD: how near are we?

Steer, Clifford J, Kren, Betsy T

Journal:

Atherosclerosis Supplements

Year:

2004

Language:

english

File:

PDF, 184 KB

english, 2004

34

Erythroid-Specific Expression of β-Globin by the Sleeping Beauty Transposon for Sickle Cell Disease †

Zhu, Jianhui, Kren, Betsy T., Park, Chang Won, Bilgim, Rasim, Wong, Phillip Y.-P., Steer, Clifford J.

Journal:

Year:

2007

Language:

english

File:

PDF, 761 KB

english, 2007

35

Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α′ subunits reduces orthotopic xenograft prostate tumors in mice

Janeen H. Trembley, Gretchen M. Unger, Diane K. Tobolt, Vicci L. Korman, Guixia Wang, Kashif A. Ahmad, Joel W. Slaton, Betsy T. Kren, Khalil Ahmed

Journal:

Molecular and Cellular Biochemistry

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

36

A Bile Acid Protects against Motor and Cognitive Deficits and Reduces Striatal Degeneration in the 3-Nitropropionic Acid Model of Huntington's Disease

C.Dirk Keene, Cecilia M.P. Rodrigues, Tacjana Eich, Cheryle Linehan-Stieers, Anna Abt, Betsy T. Kren, Clifford J. Steer, Walter C. Low

Journal:

Experimental Neurology

Year:

2001

Language:

english

File:

PDF, 446 KB

english, 2001

37

Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors

Paul W. Wacnik, Christine M. Baker, Michael J. Herron, Betsy T. Kren, Bruce R. Blazar, George L. Wilcox, Maria K. Hordinsky, Alvin J. Beitz, Marna E. Ericson

Journal:

Year:

2005

Language:

english

File:

PDF, 879 KB

english, 2005

38

1081. Targeted Nanocapsules for Liver Cell-Type Delivery of Plasmids In Vivo

Kren, Betsy T., Unger, Gretchen M., Reding, Mark T., Steer, Clifford J.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 98 KB

english, 2006

39

Transcriptional rate and steady-state changes of retinoblastoma mRNA in regenerating rat liver

Betsy T. Kren, Amy L. Teel, Clifford J. Steer

Journal:

Year:

1994

Language:

english

File:

PDF, 1.09 MB

english, 1994

40

The application of DNA repair vectors to gene therapy

Betsy T Kren, Clifford J Steer

Journal:

Current Opinion in Biotechnology

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

41

Molecular Regulation of Liver Regeneration

BETSY T. KREN, JANEEN H. TREMBLEY, GUANGSHENG FAN, CLIFFORD J. STEER

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.44 MB

english, 1997

42

Corrigendum to “Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference” [Biochem. Biophys. Res. Commun. 329 (2005) 646–652]

Zongyu J. Chen, Betsy T. Kren, Phillip Y.-P. Wong, Walter C. Low, Clifford J. Steer

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 71 KB

english, 2005

43

CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells

Ahmed, Rehana L., Shaughnessy, Daniel P., Knutson, Todd P., Vogel, Rachel I., Ahmed, Khalil, Kren, Betsy T., Trembley, Janeen H.

Journal:

Pharmaceuticals

Year:

2019

Language:

english

File:

PDF, 1.50 MB

english, 2019

44

A negative reciprocal regulatory axis between cyclin D1 and HNF4Î± modulates cell cycle progression and metabolism in the liver

Wu, Heng, Reizel, Tzachi, Wang, Yue J., Lapiro, Jessica L., Kren, Betsy T., Schug, Jonathan, Rao, Shilpa, Morgan, Ashleigh, Herman, Adam, Shekels, Laurie L., Rassette, Matthew S., Lane, Andrew N., Cas

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 1.42 MB

2020

45

Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-β1–induced apoptosis in rat hepatocytes

Susana Solá, Joana D. Amaral, Rui E. Castro, Rita M. Ramalho, Pedro M. Borralho, Betsy T. Kren, Hirotoshi Tanaka, Cifford J. Steer, Cecília M. P. Rodrigues

Journal:

Year:

2005

Language:

english

File:

PDF, 322 KB

english, 2005

46

.DELTA.22-Ursodeoxycholic Acid, a Unique Metabolite of Administered Ursodeoxycholic Acid in Rats, Indicating Partial .beta.-Oxidation as a Major Pathway for Bile Acid Metabolism

Setchell, Kenneth D. R., Yamashita, Hiroyuki, Rodrigues, Cecilia M. P., O'Connell, Nancy C., Kren, Betsy T., Steer, Clifford J.

Journal:

Year:

1995

Language:

english

File:

PDF, 2.65 MB

english, 1995

47

In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides

Kren, Betsy T., Bandyopadhyay, Paramita, Steer, Clifford J.

Journal:

Nature Medicine

Year:

1998

File:

PDF, 904 KB

1998

48

Gene repair in the new age of gene therapy

Paul D. Richardson, Betsy T. Kren, Clifford J. Steer

Journal:

Year:

2002

Language:

english

File:

PDF, 338 KB

english, 2002

49

Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration

Jingmin Shu, Betsy T. Kren, Zhilian Xia, Phillip Y.-P. Wong, Lihua Li, Eric A. Hanse, Michael X. Min, Bingshan Li, Jeffrey H. Albrecht, Yan Zeng, Subbaya Subramanian, Clifford J. Steer

Journal:

Year:

2011

Language:

english

File:

PDF, 2.24 MB

english, 2011

50

Modulation of Nuclear Steroid Receptors by Ursodeoxycholic Acid Inhibits TGF-β1-Induced E2F-1/p53-Mediated Apoptosis of Rat Hepatocytes †

Solá, Susana, Castro, Rui E., Kren, Betsy T., Steer, Clifford J., Rodrigues, Cecília M. P.

Journal:

Year:

2004

Language:

english

File:

PDF, 265 KB

english, 2004

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